NeoNat SMA Real time PCR
Real-time PCR screening for Spinal Muscular Atrophy (SMA) using dried blood spot samples.
Overview
Labsystems Diagnostics NeoNat SMA Real Time PCR is a molecular screening assay developed for the early detection of Spinal Muscular Atrophy (SMA) — a genetic disorder leading to the loss of motor function and muscle mass due to motor neuron degeneration.
The assay measures SMN1 and SMN2 gene copies directly from DNA extracted from dried blood spot (DBS) samples, enabling early identification of affected neonates and supporting timely clinical intervention.
Features
- Based on the 5’ nuclease technique
- Detects SMN1, SMN2, and globin genes (internal control)
- Includes DBS calibrators and controls for assured accuracy
- Ready-to-use reaction mix for simplified workflow
- Provides 100% specificity and sensitivity
- Compatible with multiple Real-Time PCR platforms
Technical Specifications
- Method : Real-Time PCR
- Target Genes : SMN1, SMN2, Globin (Internal Control)
- Sample Type : Dried Blood Spot (DBS)
- Controls : DBS Calibrators and Controls Included
- Reaction Mix : Ready-to-Use
- Specificity : 100%
- Sensitivity : 100%
- Instrument Compatibility : Various Real-Time PCR Instruments
Applications
- Newborn screening for Spinal Muscular Atrophy (SMA)
- Clinical and population-level screening for SMA risk assessment
Inquiry Form