Neonatal screening or Newborn Screening involves the screening of newborns in the first days of their lives for certain disorders that can hinder the normal development of the baby. These disorders, are not apparent at the time of the baby’s birth, but have potential to cause permanent neurological, cognitive, tactile and physical damage in the child. Early detection of such diseases enable initiating of suitable interventions to prevent concerning conditions in the long run. Trivitron provides a wide range Newborn Screening instruments, including Modular & Fully Automated NBS Instrumentation, manual & automated equipment and reagent kits. Trivitron's Diagnostic division Labsystems Diagnostics OY occupies the second place in the world when it comes to New Born Screening Technology.
Fluoro Enzymatic Assays
Trivitron's Labsystems Diagnostics is the first company in the world to introduce fluorometric microplate based assay for phenylalanine for diagnosing phenylketonuria (PKU) in newborns. Its pioneered Newborn Screening products and systems are based on fluorescence and photometric detections. All the reagent kits can be used manually in modular systems or in fully automated and hands off systems.
To run a successful and cost-effective newborn screening test, there is a requirement for all the instruments and reagents. Trivitron's Labsystems Diagnostics Oy delivers the most sophisticated fully-automated solutions in the highest quality and performance standards, ensuring the highest levels of performance for your lab.
Labsystems Diagnostics introduced world's first fluorometric microplate based assay for screening Phenyl Alanine in newborns to detect Phenylketonuria (PKU) and now on tandem MS along with more than 50 disorders. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) increased the screening possibilities by monitoring levels of amino acids and acylacarnitines. These tests can also be used in screening positive samples as a second tier confirmation test to differentiate between true and false positive samples. LC-MS/MS can detect several disorders with a single injection, which is important in high throughput labs.
A thyroid stimulating hormone (TSH) test is a common blood test used to evaluate how well the thyroid gland is working. For newborns and infants, thyroid hormone is crucial for normal growth and development of the body and brain. TSH Point of birth tests are routinely ordered for newborns across the world as a part of the newborn screening program to enable prompt diagnosis and treatment.