Automatic NS496 Plus
The Automatic NS496 Plus DBS Puncher is an advanced automated system designed for high-throughput processing of dried blood spot (DBS) samples. It features integrated air humidification and a clean punch mechanism to ensure precise, contamination-free punching into 96-well microtiter plates. Built for reliability and accuracy, it streamlines DBS sample preparation and improves efficiency in routine laboratory workflows.

Overview
The NS496 Plus automates the preparation of dried blood spot samples by accurately punching discs into 96-well microtiter plates. It accommodates up to four plates and allows flexible punching configurations, including multiple discs per well. With advanced automation, enhanced traceability, and optimized design, the NS496 Plus delivers consistent performance, minimal operator handling, and seamless integration into analytical workflows.

Key Features
Integrated Barcode Reader
- Provides positive identification and traceability for plates, samples, controls, and standards.
- Ensures complete traceability through the punching process with unique identification data.
Quick-Release Punch and Die Set (Mark 4)
- Allows easy removal for punch size changes or cleaning.
- Minimizes downtime and simplifies maintenance.
Disk Detector System
- Automatically detects if a disc fails to reach the receiving well.
- High-reliability beam design ensures accurate and consistent detection.
Air Humidification System
- Ensures precise disc transfer into receiving wells for downstream processing.
- Reduces static and minimizes the risk of “well jumping.”
Dedicated Cleaning Receptacle
- Designed to prevent cross-contamination and maintain system hygiene.
Technical Specifications
Enviromental Conditions
- Operating Temperature: 15°C to 35°C (59°F to 95°F)
- Operating Humidity : 35% to 80% RH, non-condensing
- Environment: : Indoor use only
Power Requirements :
- Input Voltage : 100 -240 VAC
- Frequency : 50- 60 Hz
- USB Interface : Type B connection
- Internal Fusing (24 V DC) : 3 A Anti-Surge
- Compliance : CE MDD Directive 93/42/EEC, IEC60601-1
Physical Dimensions :
- Size : 646 mm (W) × 432 mm (D) × 356 mm (H)
- Weight : 15 kg
IS Modules
The Automatic NS496 Plus comes with intelligent software modules that control every stage of operation—from test setup to configuration—ensuring accuracy, security, and user efficiency.
Main Menu
- Provides secure access to all software modules.
- Module access is password-protected at Supervisor and User levels.
Test Editor Module
- Enables definition and programming of individual tests.
- Configures punch size, number of discs, and plate filling order.
- Supports individual well definitions for samples, tests, or standards.
- Allows up to 10 discs per well.
- Includes cleaning strike configuration for improved reliability.
Distribution Module
- Executes the punching tests defined in the Test Editor.
- Displays real-time punching patterns and progress.
- Provides instrument status messages during routine operation.
Configuration Module
- Allows instrument setup, configuration, and calibration.
- Supports preference adjustments during installation.
- Supervisor-level access ensures operational control and data integrity.
