Digging deeper into the Sickle Cell Disease

Sickle cell disease is a group of hereditary disorders of the red blood cell. People suffering from sickle cell disease have an unusual protein in their RBCs. In this disease, the red blood cells are not shaped as they should be. Normally, RBCs look like round discs, but in sickle cell disease, they’re shaped like…

Knowing it all about Electrolyte Imbalance

Electrolytes are naturally occurring elements and compounds in the body that carry electrical charge. They are responsible for regulating various physiological functions. Electrolytes present in the human body are, Sodium Potassium Calcium Chloride Bi-carbonates Magnesium Phosphorus The electrolytes are present in the blood and various bodily fluids. Dietary supplements, food and water are rich in electrolytes,…

THALASSEMIA, WHEN EVERY DROP COUNTS

Thalassemia is a genetic blood disorder. People with Thalassemia disease are not able to make enough hemoglobin, which causes severe Anaemia. Hemoglobin is found in red blood cells and carries oxygen to all parts of the body. When there is not enough hemoglobin in the red blood cells, oxygen cannot get to all parts of…

Vitality of Electrophoresis in IVD

In the world of Clinical Chemistry, tests often require sophisticated equipment in addition to clinical reagents. Blood gas analysers, electrophoresis and chromatography, among others, are used alongside self-testing equipment to enable patients to self-monitor different compounds. The Electrophoresis technique is used extensively in DNA, RNA and protein analysis – wherein the technique is used to…

Understanding the major requirements of ELISA

The enzyme-linked immunosorbent assay (ELISA) is an antibody/antigen test or in simpler terms, is a test for immune response to foreign particle attacking the body like virus, bacteria and allergens. ELISA tests involve trained professionals and specialized instruments to be carried out. Among the most significant and widely used instrument to conduct ELISA test include…

The bond of blood and health

The Bond of Blood and Health

A reticulocyte count (or commonly known as retic count, corrected reticulocyte count, or reticulocyte index) is a test which doctor can use to measure the level of reticulocytes in patients’ blood.  Results obtained from the reticulocyte count can help the doctor learn if the patient’s bone marrow is producing enough red blood cells. If a…

The 4th Generation HIV Detection Kit – ELISA – For Generations to Come

 In India, mandatory screenings for HIV were implemented in the early 2000s. Since then, the Enzyme-Linked Immunosorbent Assay (ELISA) has been recommended as the preferred screening technique for HIV/AIDS and detecting antibodies produced by the body against HIV. Unlike earlier kits, ELISA uses more specific recombinant protein and synthetic peptide antigens giving highly sensitive and…