The benefits of newborn screening have not been fully understood hence, there is no coherent strategy for implementing the national screening program in India. The national level program will help to identify the infants who need urgent medical care at a much larger scale, which if left untreated may contribute significantly to the infant mortality rate. The benefits of newborn screening have not been fully understood hence, there is no coherent strategy for implementing the national screening program in India. The national level program will help to identify the infants who need urgent medical care at a much larger scale, which if left untreated may contribute significantly to the infant mortality rate.