Neonatal screening or Newborn Screening involves the screening of newborns in the first days of their lives for inborn errors of metabolism and certain disorders that can hinder the normal development of the baby. These disorders, are not apparent at the time of the baby's birth, but have potential to cause permanent neurological, cognitive, tactile and physical damage in the child. Early detection of such diseases enable initiating of suitable interventions to prevent concerning conditions in the long run. Trivitron provides a wide range Newborn Screening instruments, including Modular & Fully Automated NBS Instrumentation, manual & automated equipment and reagent kits. Trivitron's Diagnostic division Labsystems Diagnostics OY occupies the second place in the world when it comes to New Born Screening Technology.
Congenital adrenal hyperplasia (CAH) refers to a group of autosomal recessive disorders that impair cortisol biosynthesis. CAH represents a continuous phenotypic spectrum with over 95% of all cases caused by 21-hydroxylase deficiency. CAH owing to 21-hydroxylase deficiency is the most common cause of genital ambiguity in the newborn and is present in about 1 in 15,000 live births worldwide
NeoMass AAAC is used with Tandem Mass Spectrometry to detect concentrations of amino acid, free carnitine, acylcarnitines, succinylacetone and argininosuccinic acid.
Expanded newborn screening panel for quantitative determination of 15 Amino acids, free Carnitines, 12 Acylcarnitines, Argininosuccinic acid (ASA) and Succinylacetone (SUAC) under the same extraction method and single injection/single run step without using any toxic compounds, on Tandem MS